Images from this publication. In view of the potential anticancer property of the omega-3 polyunsaturated fatty acid docosahexaenoic acid DHA together with chemotherapy in estrogen receptor alpha ERα positive mammary tumors, we have explored the regulation by estradiol of the fatty acid desaturation and elongation enzymes involved in DHA synthesis in the human breast cancer cell line MCF7, which expresses ERα but not ERβ. Results shown are means ± SE of two individual experiments in duplicate. Surprisingly, WNT-5A-induced Cdc42 activation leads to decreased breast cancer cell migration and invasion. Generate a file for use with external citation management software. Add to My Bibliography. Copyright © Elsevier B.
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